How does Preimplantation Genetic Testing Improve the Success Rate of Ivf?

Preimplantation genetic testing (PGT) improves the success rates of IVF by allowing specialists to identify and select the most viable embryos for transfer. By screening embryos before they are implanted, the process addresses several factors that commonly lead to unsuccessful cycles.

Key ways PGT improves outcomes include:

• Improved Implantation Rates: By using PGT-A to screen for aneuploidy (abnormal chromosome numbers), clinicians can select embryos with the correct number of chromosomes, which are more likely to implant successfully.
• Reduced Miscarriage Risk: Chromosomal abnormalities are a leading cause of early pregnancy loss. Screening for these issues helps ensure that only chromosomally normal embryos are transferred, significantly lowering the risk of miscarriage.
• Detection of Inherited Disorders: For parents who are known carriers, PGT-M can identify single-gene disorders (such as cystic fibrosis or sickle cell disease), preventing the transmission of these conditions.
• Addressing Structural Issues: PGT-SR identifies structural chromosomal rearrangements, such as translocations or inversions, which might otherwise cause implantation failure or recurrent pregnancy loss.

While results can vary based on individual circumstances, these technologies provide a data-driven way to prioritize embryos with the highest potential for a healthy pregnancy.